Various analgesics v placebo for dysmenorrhoea*
| Weighted event rates | ||||
|---|---|---|---|---|
| Analgesic (number of trials) | Analgesic | Placebo | RBI (95% CI) | NNT (95% CI) |
| Outcome: pain relief | ||||
| Naproxen (13) | 59% | 17% | 217% (172 to 265) | 3 (2 to 4) |
| Ibuprofen (9) | 70% | 31% | 141% (58 to 268) | 3 (2 to 4) |
| Mefenamic acid (3) | 64% | 31% | 103% (65 to 148) | 3 (2 to 5) |
| Aspirin (5) | 29% | 18% | 60% (12 to 129) | 10 (6 to 50) |
| Weighted event rates | ||||
|---|---|---|---|---|
| Analgesic (number of trials) | Analgesic | Placebo | RRR (95% CI) | NNT (95% CI) |
| Outcome: use of rescue analgesics | ||||
| Naproxen (10) | 18% | 51% | 62% (56 to 68) | 4 (3 to 5) |
| Ibuprofen (2) | 13% | 57% | 77% (59 to 87) | 3 (2 to 4) |
| Aspirin (3) | 39% | 70% | 21% (−8 to 42) | Not significant |
| Weighted event rates | ||||
|---|---|---|---|---|
| Analgesic (number of trials) | Analgesic | Placebo | RRR (95% CI) | NNT (95% CI) |
| * Abbreviations defined in glossary. Data provided by author. | ||||
| Outcome: restrictions in daily life | ||||
| Naproxen (7) | 60% | 86% | 29% (15 to 40) | 5 (3 to 8) |
| Ibuprofen (3) | 12% | 55% | 74% (58 to 84) | 3 (2 to 5) |
| Aspirin (3) | 50% | 62% | 18% (−4 to 36) | Not significant |
