Article Text

PDF
Cohort study
Higher antihypertensive dose increases risk of falls in older people
  1. David S H Lee,
  2. Leah M Goeres
  1. Department of Pharmacy Practice, Oregon State University/Oregon Health & Science University College of Pharmacy, Portland, Oregon, USA
  1. Correspondence to : Dr David S H Lee, Department of Pharmacy Practice, Oregon State University/Oregon Health & Science University College of Pharmacy, 2730 Moody Ave, CH12C, Portland, OR 97201, USA; leedavid{at}ohsu.edu

Statistics from Altmetric.com

Commentary on: OpenUrlCrossRefPubMed

Implications for practice and research

  • Clinicians should be aware of the increased risk of falls with high-dose antihypertensives.

  • More clinical trials are needed to understand appropriate dose selection of antihypertensives in older patients.

Context

The recent Eighth Joint National Committee (JNC-8) guidelines have relaxed the systolic blood pressure goal for adults over 60 years to <150 mm Hg.1 These guidelines were changed because of the lack of evidence that stricter control conferred more benefits than harms.2 Research by Callisaya et al explores if higher quantification of antihypertensive medications is associated with falls in older adults, an area where mixed results are seen in the literature. …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.