Evid Based Nurs 17:86 doi:10.1136/eb-2013-101585
  • Child health
  • Cohort study

Children of mothers with iodine deficiency during pregnancy are more likely to have lower verbal IQ and reading scores at 8–9 years of age

  1. Gregory A Brent
  1. Division of Endocrinology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA
  1. Correspondence to : Dr Angela M Leung, Division of Endocrinology 111D, Department of Medicine, 11301 Wilshire Blvd, Los Angeles, CA 90073, USA; amleung{at}

Commentary on:

Implications for practice and research

  • Children of mothers with iodine deficiency during the early pregnancy have an increased risk of impaired cognitive development at 8–9 years of age, even after adjustment for potential confounding factors.

  • Among iodine-deficient women, the child's cognitive scores showed a downward trend with a decreasing maternal iodine intake.

  • Further research is warranted to confirm the present findings.


Iodine deficiency is one of the leading causes of preventable brain damage. Although the relationship between maternal severe iodine deficiency and impaired cognitive function in children is well-established, less is …

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