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Cohort study
People with HIV are at increased risk of acute myocardial infarction
  1. Jens D Lundgren
  1. Department of Infectious Diseases, Rigshospitalet—Copenhagen University Hospital, Copenhagen, Denmark
  1. Correspondence to: Jens D Lundgren
    Department of Infectious Diseases, Rigshospitalet—Copenhagen University Hospital, Blegdamsvej 9, Copenhagen 2100, Denmark; jdl{at}cphiv.dk

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Implications for practise and research

  • HIV seropositive status adds to the risk of coronary heart disease.

  • This will have an impact on the morbidity and mortality patterns of persons who are HIV-positive (HIV+) as they age.

  • The reasons as to why this excess risk exists and what rational interventions should be used to reduce the risk remain key areas of research.

Context

The continued use of antiretroviral therapy (ART) allows persons who are HIV+ to survive to an age where the risk of cardiovascular disease (CVD) in the general population is prominent. Traditional risk factors drive the risk of CVD in persons who are HIV+ to an extent comparable with the general population. These risk factors (eg, smoking, diabetes and dyslipidaemia) are seen more frequently …

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