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Randomised controlled trial
Preoperative skin cleansing with chlorhexidine-alcohol reduces surgical site infection after clean-contaminated surgery compared with povidone-iodine
  1. Olivier Mimoz
  1. CHU de Poitiers, INSERM ERI 23 and Université de Poitiers, Poitiers, France
  1. Correspondence to Olivier Mimoz
    Réanimation Chirurgicale Polyvalente, CHU de Poitiers, 86021 Poitiers Cedex, France; o.mimoz{at}chu-poitiers.fr

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More than 30 million operative procedures are performed each year in the USA.1 Despite the implementation of a bundle of preventive measures such as preoperative use of hair clippers or no hair removal (as opposed to shaving), initial administration of perioperative antibiotics within 1 hour before surgery, and maintenance of normothermia, normoglycaemia and hyperoxia during surgery and for the first 2 hours after surgery, between 300 000 and 500 000 patients develop a surgical site infection (SSI). These infections increase length of hospital stay, hospital costs and mortality.2 A patient's skin is a major source of micro-organisms; reducing the pathogens at the operating site by improving skin antisepsis may help decrease the …

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