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Evid Based Nurs 13:17 doi:10.1136/ebn1016
  • Therapeutics
  • Systematic review

Preventive antibiotics reduce infections but not mortality in adults with acute stroke

  1. Peter Langhorne
  1. Professor Peter Langhorne
    Academic Section of Geriatric Medicine, Division of Cardiovascular and Neurological Sciences, University of Glasgow, Glasgow G4 0SF, UK; P.Langhorne{at}clinmed.gla.ac.uk

Commentary on: van de Beek D, Wijdicks EF, Vermeij FH, et al. Preventive antibiotics for infections in acute stroke: a systematic review and meta-analysis. Arch Neurol 2009;66:1076–81.

Infection is a common complication in acute stroke1 and can affect patients with either cerebral infarction or cerebral haemorrhage. In most observational studies (such as those by Langhorne and colleagues2 and Aslanyan and colleagues3) the commonest post-stroke infections are of the chest (pneumonia) and of the urinary tract. These two infections can affect up to 20% of patients in the first few …

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