Evid Based Nurs 12:121 doi:10.1136/ebn.12.4.121
  • Causation

Review: anger and hostility increase risk of coronary heart disease events in healthy people and those with existing CHD


Are personality traits of anger and hostility associated with increased risk of coronary heart disease (CHD) events in healthy people or those with existing CHD?

Review scope

Included studies evaluated the association between anger and hostility and future CHD events in healthy people and people with CHD. Studies evaluating the effect of acute anger were excluded. Outcomes were CHD events (including CHD mortality, non-fatal myocardial infarction, angina, cardiac arrest, and coronary artery restenosis).

Review methods

Medline, PsycINFO, Web of Science, and PubMed (to Nov 2008); and references were searched for prospective cohort studies published as full-length English-language articles in peer-reviewed journals. 38 articles involving 25 cohorts of healthy people (n = 71 606, duration of follow-up 2–47 …

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