Evid Based Nurs 12:115 doi:10.1136/ebn.12.4.115
  • Treatment

Intravascular catheter dressings with chlorhexidine-impregnated sponges reduced infections in the ICU


Do intravascular catheter dressings with chlorhexidine gluconate–impregnated sponges (CHGISs) reduce catheter-related infections (CRIs) compared with standard dressings in intensive care unit (ICU) patients? Are dressing changes every 7 days non-inferior to changes every 3 days?



2 × 2 factorial randomised controlled trial. NCT00417235.




blinded (microbiologists, outcome assessors, {data analysts, and safety committee}*).

Follow-up period:

48 hours after ICU discharge.


7 ICUs in 3 university and 2 general hospitals in France.


1653 patients >18 years of age (median age 62 y, 64% men, based on 1636 patients) requiring catheters for ⩾48 hours. Exclusion criteria were allergy to chlorhexidine or transparent dressings.


CHGIS dressings, 3-day change (n = 412); CHGIS dressings, 7-day change (n = 413); standard dressings, 3-day change (n = 416); or standard dressings, 7-day change (n = 412). In all …

No Related Web Pages

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article