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Does vaginal douching increase risk of sexually transmitted infections (STIs) in high-risk adolescents?
prospective cohort study (substudy of Reaching for Excellence in Adolescent Care and Health [REACH] Project) with median follow-up of 3 years.
16 centres in the USA.
368 females 12–19 years of age (mean age 17 y, 65% had HIV infection) who were considered to be at high risk of STIs and were STI-free at baseline or became STI-free after treatment.
douching status (assessed every 6 mo): never (did not report douching at any visit), intermittent (reported douching at some, but not all, visits), or always (reported douching at all visits).
incidence of an STI (Trichomonas vaginalis, Chlamydia trachomatis, Neisseria gonorrhoeae, or herpes …