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Intensive nutritional supplementation improved functional outcome after stroke

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QUESTION

Does an intensive nutritional supplement improve functional outcome in undernourished patients in a stroke rehabilitation unit?

METHODS

Design:

randomised controlled trial.

Allocation:

concealed.

Blinding:

blinded (patients, healthcare providers, therapists, data collectors, and outcome assessors).

Follow-up period:

to discharge (mean 26 d).

Setting:

stroke rehabilitation unit in New York, USA.

Patients:

116 patients (mean age 74 y, 59% men) who had had a first stroke <4 weeks before admission to the unit, had ⩾2.5% weight loss within 2 weeks after the stroke, were medically stable, and were able to ingest food orally. Exclusion criteria were dementia, alcohol abuse, renal or liver disease, malabsorption, and terminal illness.

Intervention:

intensive nutritional supplement (240 calories, 11 g of protein) (n = 58) or standard nutritional supplement (127 calories, 5 g of protein) (n = 58), 120 …

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