Article Text

Download PDFPDF
Review: pneumococcal vaccination does not prevent pneumonia, bacteraemia, bronchitis, or mortality

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

QUESTION

Is pneumococcal vaccination effective for various clinical outcomes in adults?

REVIEW SCOPE

Included studies compared pneumococcal polysaccharide vaccine with placebo, other vaccines, or no intervention (control). Studies of children; evaluating antibody responses only or pneumococcal polysaccharide vaccines as a booster after receipt of conjugate pneumococcal vaccine; or animal, laboratory, and observational intervention studies were excluded. Outcomes were definitive pneumococcal pneumonia, presumptive pneumococcal pneumonia, all-cause pneumonia, bacteraemia, bronchitis, all-cause mortality, pneumonia mortality, and mortality from pneumococcal infection.

REVIEW METHODS

Medline (1966 to May 2007), EMBASE/Excerpta Medica (1974 to May 2007), Cochrane Central Register of Controlled Trials, Latin American and Caribbean Health Sciences Literature, Indian Medlars Centre, African Index Medicus, …

View Full Text

Footnotes

  • Source of funding: World Health Organization.