Evid Based Nurs 12:49 doi:10.1136/ebn.12.2.49
  • Treatment

Review: immediate antiplatelet therapy after acute ischaemic stroke reduces death or dependency and risk of recurrent stroke

P A Sandercock

Dr P A Sandercock, University of Edinburgh, Edinburgh, UK;


What is the efficacy and safety of immediate antiplatelet therapy after acute ischaemic stroke?


Included studies compared antiplatelet therapy, including aspirin, abciximab, heparin, and ticlopidine (started within 14 d of stroke) with placebo or no treatment in patients with acute ischaemic stroke. Studies of antiplatelet therapy after primary intracerebral or subarachnoid haemorrhage, or drugs with multiple modes of action (eg, piracetam, prostacyclin, and oxpentifylline) were excluded. Outcomes included death or dependence on others for activities of daily living 1 month after stroke, all-cause mortality, deep venous thrombosis, pulmonary embolism, recurrent stroke, and intracranial and extracranial haemorrhage.


Medline, EMBASE/Excerpta Medica, …

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article