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Continuous glucose monitoring improved glycaemic control in pregnant women with diabetes and reduced infant macrosomiaCommentary

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H R Murphy

Dr H R Murphy, University of Cambridge, Cambridge, UK; hm386@medschl.cam.ac.uk

QUESTION

Does continuous glucose monitoring (CGM) improve glycaemic control in pregnant women with diabetes and reduce infant macrosomia?

METHODS

Design:

randomised controlled trial. Current Controlled Trials ISRCTN84461581.

Allocation:

concealed.

Blinding:

unblinded.

Follow-up period:

to delivery.

Setting:

2 diabetes antenatal clinics in the UK.

Patients:

71 pregnant women (mean age 31 y, mean gestational age 9 wks) who had type 1 diabetes (65% of women) or type 2 diabetes (35%) treated with insulin.

Intervention:

CGM plus standard antenatal care (n = 38) or standard care alone (n = 33). CGM was done every 4–6 weeks until 32 weeks of gestation. A subcutaneous sensor, attached to a portable monitor, was implanted by a nurse into the woman’s hip and worn for 5–7 days. The device recorded average tissue glucose concentrations every 5 minutes, but results …

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