You are here

  • Home
  • Archive
  • Volume 12, Issue 2
  • Paracetamol plus ibuprofen increased time without fever compared with paracetamol but did not differ from ibuprofen in childrenCommentary

Article Text

Article menu
Download PDFPDF
Treatment
Paracetamol plus ibuprofen increased time without fever compared with paracetamol but did not differ from ibuprofen in children

https://doi.org/10.1136/ebn.12.2.41

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    A D Hay

    Dr A D Hay, University of Bristol, Bristol, UK; alastair.hay@bristol.ac.uk

    QUESTION

    How does paracetamol (PCM) plus ibuprofen (IBF) compare with either drug alone for treating fever in children?

    METHODS

    Design:

    randomised controlled trial (Paracetamol plus Ibuprofen for the Treatment of fever in CHildren [PITCH]). Current Controlled Trials ISRCTN26362730.

    Allocation:

    concealed.

    Blinding:

    blinded (nurses, {patients, data collectors, outcome assessors, data analysts, and safety committee}*).

    Follow-up period:

    48 hours.

    Setting:

    35 primary care sites in Bristol, UK.

    Patients:

    156 children (mean age 2 y, age range 6 mo to 6 y, 56% boys) who had axillary temperatures of 37.8°C to 41°C. Exclusion criteria included need for hospital admission; dehydration; chronic disease; or contraindication to trial …

    View Full Text

    Footnotes

    • Source of funding: National Institute for Health Research and National Coordinating Centre for Health Technology Assessment.