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Review: short-term medical use of cannabis increases risk of non-serious adverse effectsCommentary

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M A Ware

Dr M A Ware, Montreal General Hospital, Montreal, Quebec, Canada; mark.ware@mail.mcgill.ca

QUESTION

Is medical use of cannabis associated with an increased risk of adverse effects?

REVIEW SCOPE

Studies selected reported adverse events associated with medical use of cannabis for pain or chemotherapy-induced nausea in patients with chronic diseases such as multiple sclerosis, neuropathic pain, or cancer. Outcomes were serious and non-serious adverse events.

REVIEW METHODS

Ovid Medline, PsycINFO, and EMBASE/Excerpta Medica (to Oct 2007), and reference lists were searched for randomised controlled trials (RCTs), observational studies, and case reports. 23 RCTs (n = 2087) and 8 observational studies met the selection criteria. …

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