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Intensive glucose control increased mortality and did not prevent cardiovascular events in type 2 diabetes

https://doi.org/10.1136/ebn.12.1.13

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    R P Byington

    Dr R P Byington, Wake Forest University School of Medicine, Winston-Salem, NC, USA; bbyingto@wfubmc.edu

    QUESTION

    In patients with type 2 diabetes and cardiovascular disease or risk factors, does intensive glucose control prevent cardiovascular events more than standard glucose control?

    METHODS

    Design:

    randomised controlled trial (Action to Control Cardiovascular Risk in Diabetes [ACCORD]).

    Allocation:

    concealed.

    Blinding:

    blinded (outcome adjudication committee and …

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    Footnotes

    • Source of funding: National Institutes of Health; Centers for Disease Control and Prevention; General Clinical Research Centers.