Article Text

PDF
Protocol-directed sedation did not reduce duration of mechanical ventilation or hospital stay in ICU patients

Statistics from Altmetric.com

T K Bucknall

Dr T K Bucknall, Deakin University, Burwood, Victoria, Australia; [email protected]

QUESTION

Does protocol-directed sedation reduce duration of mechanical ventilation in intensive care units (ICUs)?

METHODS

Design:

randomised controlled trial.

Allocation:

concealed.

Blinding:

blinded {data collectors, outcome assessors, and data analysts}.*

Follow-up period:

duration of hospital stay.

Setting:

a 24-bed, university-affiliated, mixed medical-surgical-trauma ICU in Australia.

Patients:

316 adults who were mechanically ventilated. Patients admitted after cardiac surgery or who were previously enrolled in the study were excluded.

Intervention:

155 patients were allocated to the sedation protocol, which specified medications to be prescribed to achieve a Sedation Agitation Scale (SAS) target. Nurses determined sedation and analgesia type, dose, and method of administration to provide optimal care consistent with the protocol. 161 patients were allocated to usual sedation practice, which …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.