Negative pressure wound therapy promoted healing of diabetic foot ulcers more than advanced moist wound therapy
P A Blume
Dr P A Blume, North American Center for Limb Preservation, New Haven, CT, USA; firstname.lastname@example.org
Is negative pressure wound therapy (NPWT) using vacuum-assisted closure more effective than advanced moist wound therapy (AMWT) for diabetic foot ulcers?
randomised controlled trial.
16 weeks (efficacy) and 26 weeks (safety).
29 diabetic foot and wound clinics in the USA and Canada. Treatment occurred mainly at home (92% of treatment days).
341 patients ⩾18 years of age (mean age 58 y, 79% men) with adequately controlled diabetes who had a stage 2 or 3 calcaneal, dorsal, or plantar foot ulcer ⩾2 cm2 in area after debridement and adequate lower extremity perfusion. Exclusion criteria included active Charcot disease, collagen vascular disease, ulcer …