Evid Based Nurs 11:91 doi:10.1136/ebn.11.3.91
  • Clinical prediction guide

QRISK underestimated risk of cardiovascular disease in general practice patients; Framingham score overestimated risk

J Hippisley-Cox

Prof J Hippisley-Cox, University Park, Nottingham, UK;


Does QRISK score predict risk of cardiovascular disease (CVD) in a validation sample of general practice patients? How does it compare with Framingham score?



prospective cohort study.


2 validation cohorts from general practices in the UK that provided routinely collected clinical data to 1 of 2 research databases (QRESEARCH, n = 160; THIN, n = 274).


patients who were included in the THIN (n = 1.07 million) or QRESEARCH (n = 0.61 million) databases, were 35–74 years of age (51% women), did not have diabetes or CVD, and were not taking statins at baseline.

Description of prediction guide:

QRISK score included traditional risk factors (age, sex, systolic blood pressure, smoking status, and total/high density lipoprotein serum cholesterol ratio) as well as social deprivation …

No Related Web Pages

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article