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A Jull
Dr A Jull, University of Auckland, Auckland, New Zealand; a.jull@ctru.auckland.ac.nz
QUESTION
Is honey effective for the management of venous leg ulcers?
METHODS
Design:
randomised controlled trial (Honey as Adjuvant Leg Ulcer Therapy [HALT] trial).
Allocation:
concealed.
Blinding:
blinded (outcome assessor).
Follow-up period:
12 weeks.
Setting:
4 community-based district nursing services in Auckland, South Auckland, Waikato, and Christchurch, New Zealand.
Patients:
368 patients (mean age 68 y, 51% women) who had venous ulcers or mixed venous and arterial ulcers and could tolerate compression. Exclusion criteria were history of diabetes, rheumatoid arthritis or peripheral arterial disease, allergy to calcium alginate or manuka honey, and current honey treatment.
Intervention:
calcium alginate dressings impregnated with manuka honey (n = 187) or usual care (a range of dressings) (n = 181). All patients received compression bandaging. Honey dressings were changed when compression bandaging was changed.
Outcomes:
included complete healing at 12 weeks (defined as complete …