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Evid Based Nurs 11:47 doi:10.1136/ebn.11.2.47
  • Treatment

Review: topical permethrin was more effective than topical crotamiton or lindane for scabies

M Strong

Dr M Strong, University of Sheffield, Sheffield, UK; m.strong@sheffield.ac.uk

QUESTION

Which topical or systemic drugs are effective for scabies?

METHODS

Data sources:

Medline, EMBASE/Excerpta Medica, LILACS, INDMED, and Cochrane Infectious Diseases Group Specialised Register (all to February 2007); Cochrane Central Register of Controlled Trials (Cochrane Library, Issue 1, 2007); websites of registered clinical trials and grey literature sources (March 2007); and reference lists.

Study selection and assessment:

randomised controlled trials (RCTs) that compared systemic or local drug treatment with placebo, no intervention, or a different intervention or combination of interventions in children or adults with a clinical or parasitological diagnosis of scabies, or their contacts. 20 RCTs (n = 2392, follow-up range 1 …

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