Evid Based Nurs 10:111 doi:10.1136/ebn.10.4.111
  • Treatment

The Atkins diet led to more weight loss than the Zone diet in overweight and obese premenopausal women at 12 months

 Q What is the relative effectiveness of Atkins, Zone, “Lifestyle, Exercise, Attitudes, Relationships, and Nutrition (LEARN),” and Ornish diets for weight loss in overweight or obese premenopausal women?



randomised controlled trial (Atkins, Traditional, Ornish, Zone [A TO Z] Weight Loss Study).


unclear allocation concealment.


blinded {data collectors, data analysts, and safety and monitoring committee}.*

GraphicFollow-up period:

12 months.


United States.


311 premenopausal women 25–50 years of age (mean age 41 y, 71% white) who were overweight or obese (body mass index [BMI] 27–40 kg/m2), had stable weight in the past 2 months, and stable medications for ⩾3 months. Exclusion criteria included diabetes; hyperthyroidism; hypertension; heart, renal, or liver disease; cancer; use of drugs affecting weight or energy expenditure; ⩾3 drinks of alcohol/day; pregnancy; lactation; and …

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