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Including a weaning predictor in the daily assessment of weaning readiness increased mechanical ventilation weaning time

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 Q In patients receiving mechanical ventilation, does including a weaning predictor in the daily assessment of weaning readiness reduce weaning time?

METHODS

Embedded ImageDesign:

randomised controlled trial.

Embedded ImageAllocation:

concealed.

Embedded ImageBlinding:

blinded (patients, healthcare providers, and respiratory therapists). The respiratory care practitioner who assessed readiness for weaning was not blinded.

Embedded ImageFollow up period:

to hospital discharge or death.

Embedded ImageSetting:

intensive care units (ICUs) of 3 hospitals in the US and Canada.

Embedded ImagePatients:

304 patients >18 years of age (mean age 65 y, 54% men) who had acute respiratory failure and had been on mechanical ventilation for ⩾24 hours (median 2 d). Exclusion criteria included expected survival <48 hours and primary neurological event without expectation for recovery.

Embedded ImageIntervention:

all patients underwent a daily screen by a respiratory care practitioner to assess readiness for weaning from the ventilator, including measurement of frequency tidal volume ratio …

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