rss
Evid Based Nurs 10:87 doi:10.1136/ebn.10.3.87
  • Treatment

4 layer bandages were better than 1 layer bandages, and pentoxifylline may be better than placebo for venous leg ulcers


 
 Q In patients with venous leg ulcers, which drug, bandage, and dressing options are most effective for healing?

METHODS

GraphicDesign:

2×2×2 factorial randomised controlled trial.

GraphicAllocation:

concealed.

GraphicBlinding:

partially blinded (patients and healthcare providers were blinded to the drug intervention only).

GraphicFollow up period:

24 weeks.

GraphicSetting:

2 centres in Scotland, UK.

GraphicPatients:

245 patients >18 years of age (mean age 70 y, 67% women) with clinical signs of venous disease and a venous leg ulcer ⩾1 cm in length and ⩾8 weeks in duration. Exclusion criteria included important arterial disease, diabetes, and infected or gangrenous ulcers.

GraphicInterventions:

pentoxifylline, sustained release 400 mg 3 times daily, (n = 121) or placebo (n = 124); 4 layer bandage (n = 117) or adhesive 1 layer bandage (n = 128); and …

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article