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Evid Based Nurs 10:80 doi:10.1136/ebn.10.3.80
  • Treatment

Review: adequately randomised trials showed that mammography screening did not significantly reduce breast cancer, cancer, or all cause mortality but increased breast surgeries


 
 Q Does screening for breast cancer with mammography reduce morbidity and mortality?

METHODS

GraphicData sources:

PubMed (June 2005) and review of reference lists.

GraphicStudy selection and assessment:

randomised controlled trials (RCTs) that compared mammography screening with no mammography screening in women without previously diagnosed breast cancer. 7 trials met the selection criteria; 2 had adequate randomisation, 4 had sub-optimal randomisation, and 1 was not adequately randomised. Separate analyses were done for adequately and sub-optimally randomised trials.

GraphicOutcomes:

breast cancer mortality, cancer mortality, all cause mortality, surgical interventions, and adjuvant therapy.

MAIN RESULTS

Meta-analysis showed that mammography screening reduced breast cancer mortality at 7 and 13 years; however, meta-analysis …

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