Review: lifestyle or pharmacological interventions prevent or delay type 2 diabetes in people with impaired glucose tolerance
Q In people with impaired glucose tolerance, do lifestyle or pharmacological interventions prevent or delay type 2 diabetes?
METHODS
Data sources:
Medline (1966 to July 2006), EMBASE/Excerpta Medica (1980 to July 2006), Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews (Issue 2, 2006), references of relevant articles, and experts.
Study selection and assessment:
randomised controlled trials (RCTs) in any language that evaluated an intervention to delay or prevent type 2 diabetes in people with impaired glucose tolerance and assessed development of diabetes as an outcome. 21 RCTs met the selection criteria, and 17 RCTs (n = 8084, mean age range 39–57 y, mean body mass index range 24–36 kg/m2, …
