Article Text
Treatment
Review: antihistamines, decongestants, or both do not provide benefit in children with otitis media with effusion
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Q Are antihistamines, decongestants, or both effective in treating children with otitis media with effusion (OME)?
METHODS
Data sources:
Cochrane Ear, Nose, and Throat Disorders Group Trials Register, Cochrane Central Register of Controlled Trials, Medline (1951–2006), EMBASE/Excerpta Medica (1974–2006), grey literature database, references of included trials and relevant reviews, manufacturers of decongestants and antihistamines, and authors in the field.
Study selection and assessment:
randomised controlled trials (RCTs) comparing oral or nasal decongestants or antihistamines with no medication or placebo in children ⩽18 years of age with OME. Trials in which the data of patients with acute otitis media, anatomical deformity, or other chronic …