Evid Based Nurs 10:49 doi:10.1136/ebn.10.2.49
  • Treatment

Review: inhaled insulin provides better glycaemic control than oral hypoglycaemic agents but not better than subcutaneous insulin

 Q In patients with diabetes, what is the relative efficacy, safety, and acceptability of inhaled insulin compared with subcutaneous (SC) insulin and oral hypoglycaemic agents?


GraphicData sources:

Medline (June 2006), Cochrane Controlled Clinical Trials Register (Issue 2, 2006), reference lists, and the US Food and Drug Administration web site.

GraphicStudy selection and assessment:

English language randomised controlled trials (RCTs) that compared inhaled insulin with SC insulin or oral hypoglycaemic agents in non-pregnant adults with type 1 or type 2 diabetes and had a duration ⩾12 weeks. 16 RCTs (n = 4023, mean age range 29–60 y, 58% men) met the selection criteria. Methodological quality was assessed based on randomisation method, intention to treat analysis, dropout rate, and primary outcome (efficacy or safety).


change in haemoglobin A1c (HbA1c …

No Related Web Pages

Free Sample

This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of EBN.
View free sample issue >>

EBN Journal Chat

The EBN Journal Chat offers readers the opportunity to participate in discussion about research articles and commentaries from Evidence Based Nursing (EBN).

How to participate >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Navigate This Article