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Review: antibiotics are effective for acute purulent rhinitis but are associated with increased gastrointestinal side effects

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Q Are antibiotics effective and safe for acute purulent rhinitis?

METHODS

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Medline, EMBASE/Excerpta Medica, Cochrane Register of Controlled Trials (up to November 2005), bibliographies of published reviews, and authors.

Embedded ImageStudy selection and assessment:

randomised controlled trials (RCTs) that compared antibiotics with placebo in patients of any age with acute purulent rhinitis (duration <10 d). Studies of patients with sinusitis were excluded. 7 RCTs met the selection criteria; 6 RCTs (n = 1647, age >2 mo) were included in the quantitative analysis; 2 RCTs …

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