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  • Review: antibiotics are effective for acute purulent rhinitis but are associated with increased gastrointestinal side effects

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Review: antibiotics are effective for acute purulent rhinitis but are associated with increased gastrointestinal side effects

https://doi.org/10.1136/ebn.10.1.9

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    Arroll B, Kenealy T. Are antibiotics effective for acute purulent rhinitis? Systematic review and meta-analysis of placebo controlled randomised trials. BMJ 2006;333:279.OpenUrlAbstract/FREE Full Text

    Q Are antibiotics effective and safe for acute purulent rhinitis?

    METHODS

    Embedded ImageData sources:

    Medline, EMBASE/Excerpta Medica, Cochrane Register of Controlled Trials (up to November 2005), bibliographies of published reviews, and authors.

    Embedded ImageStudy selection and assessment:

    randomised controlled trials (RCTs) that compared antibiotics with placebo in patients of any age with acute purulent rhinitis (duration <10 d). Studies of patients with sinusitis were excluded. 7 RCTs met the selection criteria; 6 RCTs (n = 1647, age >2 mo) were included in the quantitative analysis; 2 RCTs …

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    Footnotes

    • For correspondence: Professor B Arroll, Department of General Practice and Primary Health Care, University of Auckland, Auckland, New Zealand. b.arroll{at}auckland.ac.nz

    • Source of funding: no external funding.