Review: a low protein diet delays end stage renal disease or death in chronic kidney disease
Q In patients with chronic kidney disease, does a low protein diet delay progression to end stage renal disease or death?
Cochrane Central Register of Controlled Trials, Cochrane Renal Group Trials Register, Medline, EMBASE/Excerpta Medica, conference abstracts from 3 nephrology associations, and authors in the field.
Study selection and assessment:
randomised controlled trials (RCTs) that compared moderately to severely restricted protein intake (0.3–0.6 g/kg per d) with standard protein intake (⩾0.8 g/kg per d) in patients with moderate to severe chronic kidney disease. Trials of children or patients with diabetes were excluded. 8 RCTs (n = 1524, mean age range 48–62 y) met the selection criteria. Details of …