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Evid Based Nurs 1:118 doi:10.1136/ebn.1.4.118
  • Treatment

A non-prescription analgesic alleviated migraine headache pain and symptoms

Acetaminophen, aspirin, and caffeine (active drugs) v placebo for migraine headache

Outcomes Active drugs Placebo RBI (95% CI) NNT (CI)
*Abbreviations defined in glossary; RBI, NNT, and CI calculated from data in article.
Reduced pain at 2 h 59% 33% 81% (59 to 106) 4 (3 to 5)
Reduced pain at 6 h 79% 52% 52% (40 to 66) 4 (3 to 5)
No pain at 2 h 21% 7% 192% (111 to 304) 8 (6 to 10)
No pain at 6 h 51% 24% 117% (84 to 155) 4 (3 to 5)
No rescue drugs by 6 h 88% 73% 20% (14 to 27) 7 (5 to 10)

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