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Dietary fibre intake was not associated with a lower risk of colorectal cancer in women

https://doi.org/10.1136/ebn.2.3.89

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    Fuchs CS, Giovannucci EL, Colditz GA, et al. Dietary fiber and the risk of colorectal cancer and adenoma in women.N Engl J Med1999 Jan 21; 340:169–76.OpenUrlCrossRefPubMedWeb of Science

    Question Is dietary fibre intake associated with a decreased risk of colorectal cancer and adenoma in women?

    Design

    Prospective, population based cohort study of women in the Nurses' Health Study with 16 years of follow up.

    Setting

    United States.

    Participants

    88 757 women who were nurses between 30 and 55 years of age in 1976. Exclusion criteria were cancer other than non-melanoma skin cancer, ulcerative colitis, Crohn's disease, familial polyposis syndrome, implausible high or low scores for total energy intake, or missing food frequency questionnaire data.

    Assessment of risk factors

    Nurses completed mailed questionnaires at baseline and every 2 years thereafter. Food frequency questionnaires included information on 61 foods, beverages, and vitamin and mineral supplements. For analysis, nurses were divided into quintiles based on energy adjusted …

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    Footnotes

    • Source of funding: National Institutes of Health.

    • For correspondence: Dr C S Fuchs, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA. Fax +1 617 632 5370.