© 2000 Evidence-Based Nursing
EBN notebook
Estimating treatment effects: real or the result of chance?
Department of Health Studies University of York, York, UK
The Notebook in the January 2000 issue of Evidence-Based Nursing described how the outcomes of clinical trials are measured and summarised before analysis. We now discuss how we can tell, by using and interpreting statistical tests, if treatments have a real effect on health or if the apparent effects of treatments under trial are a result of chance.When critically reading a report of a clinical trial, one of the things we are interested in is whether the results of the study provide an accurate estimate of the true treatment effect in the type of patients included in the study.
Even if a study has been carried out in a methodologically sound (unbiased) way, a study result such as "5% more wounds healed in the treatment compared with the control group" does not necessarily mean that this is a true treatment effect. This finding could be a chance occurrence
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