TREATMENT
A very low calorie diet plus lifestyle counselling improved mild obstructive sleep apnoea in overweight patients
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Does a very low calorie diet (VLCD) plus intensive lifestyle counselling improve mild obstructive sleep apnoea (OSA) in overweight patients?
randomised controlled trial (RCT).
unclear allocation concealment.
blinded (outcome assessors).
1 year.
Kuopio University Hospital, Kuopio, Finland.
81 patients 18–65 years of age (mean age 51 y, 65% men) who had a body mass index of 28–40 kg/m2 and an apnoea-hypopnoea index (AHI) of 5–15 events/hour. Exclusion criteria were active treatment for OSA, pregnancy, and chronic kidney, thyroid, or liver disease.
a VLCD (600–800 kcal/d) for 12 weeks plus intensive lifestyle counselling for 1 year (n = 40) or general oral and written information about diet and exercise at baseline, 3-month, and 1-year visits (control) (n = 41).
included mild OSA and changes in weight, AHI, Snore Outcomes Survey (SOS), and Epworth Sleepiness Scale (ESS).
89% (intention-to-treat analysis).
Fewer patients in the VLCD plus counselling group had mild OSA than
University of Manitoba, Faculty of Nursing, Winnipeg, Manitoba, Canada
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