TREATMENT
Review: inhaled corticosteroids reduce wheezing and asthma exacerbations in infants and preschool children
| The first 150 words of the full text of this article appear below. |
Do inhaled corticosteroids (ICSs) reduce wheezing/asthma exacerbations (WAEs) in infants and preschool children with a previous diagnosis of wheezing or asthma?
Included studies were randomised controlled trials (RCTs) of 
4 weeks of treatment that compared an ICS with placebo in infants and children 
5 years of age with a diagnosis of wheezing or asthma for 6 months before study entry. Outcomes were WAEs (worsening symptoms that required systemic corticosteroids), withdrawal from study due to WAEs, change in symptom score, change in salbutamol(albuterol) use, and change in pulmonary function (FEV1 and peak expiratory flow [PEF]).
Medline, EMBASE/Excerpta Medica, and Cochrane Central Register of Controlled Trials (all to Mar or second quarter 2008) were searched for RCTs. 29 RCTs {n = 3992, mean age 40 mo}* met the selection criteria. Jadad quality scores ranged from 2 to 5 (mean 3.5) out of 5.
ICSs decreased the incidence of WAEs, withdrawals from study
School of Nursing, University of Auckland, Auckland, New Zealand
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
