CAUSATION
Vaginal douching increased risk of sexually transmitted infections in high-risk adolescents
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Does vaginal douching increase risk of sexually transmitted infections (STIs) in high-risk adolescents?
Design: prospective cohort study (substudy of Reaching for Excellence in Adolescent Care and Health [REACH] Project) with median follow-up of 3 years.
Setting: 16 centres in the USA.
Participants: 368 females 12–19 years of age (mean age 17 y, 65% had HIV infection) who were considered to be at high risk of STIs and were STI-free at baseline or became STI-free after treatment.
Risk factor: douching status (assessed every 6 mo): never (did not report douching at any visit), intermittent (reported douching at some, but not all, visits), or always (reported douching at all visits).
Outcomes: incidence of an STI (Trichomonas vaginalis, Chlamydia trachomatis, Neisseria gonorrhoeae, or herpes simplex virus type 2) assessed by laboratory testing of urine, anal, and endocervical samples every 6 months.
Douching status over the entire follow-up period was
University of Texas at Austin Austin, Texas, USA
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