TREATMENT
Review: insufficient evidence exists for oral nutritional supplements as aids for recovery in treated active tuberculosis
| The first 150 words of the full text of this article appear below. |
In patients being treated for active tuberculosis, do oral nutritional supplements aid recovery?
Included studies compared oral nutritional supplements taken for
4 weeks with no nutritional intervention, placebo, or dietary advice in children or adults being treated with drugs for active tuberculosis. Outcomes included death, positive sputum tests, and weight change.
Cochrane Infectious Disease Group Specialised Register, Medline, EMBASE/Excerpta Medica, LILACS, metaRegister of Controlled Trials (all to Jun 2008), Cochrane Central Register of Controlled Trials (Cochrane Library, Issue 2, 2008), Indian J Tuber (1983 to Jun 2008), and reference lists were searched for randomised controlled trials (RCTs). 12 RCTs (n = 3393) met the selection criteria: 3 used multiple micronutrient supplements, including 1 with additional zinc; 3 used vitamin D; 3 used vitamin A alone or with zinc or selenium; and 1 each used arginine, zinc, high energy protein, and a high cholesterol diet. 5 trials reported adequate
University of Missouri, Sinclair School of Nursing, Columbia, Missouri, USA
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