TREATMENT
Review: pneumococcal vaccination does not prevent pneumonia, bacteraemia, bronchitis, or mortality
| The first 150 words of the full text of this article appear below. |
Is pneumococcal vaccination effective for various clinical outcomes in adults?
Included studies compared pneumococcal polysaccharide vaccine with placebo, other vaccines, or no intervention (control). Studies of children; evaluating antibody responses only or pneumococcal polysaccharide vaccines as a booster after receipt of conjugate pneumococcal vaccine; or animal, laboratory, and observational intervention studies were excluded. Outcomes were definitive pneumococcal pneumonia, presumptive pneumococcal pneumonia, all-cause pneumonia, bacteraemia, bronchitis, all-cause mortality, pneumonia mortality, and mortality from pneumococcal infection.
Medline (1966 to May 2007), EMBASE/Excerpta Medica (1974 to May 2007), Cochrane Central Register of Controlled Trials, Latin American and Caribbean Health Sciences Literature, Indian Medlars Centre, African Index Medicus, and reference lists were searched for randomised controlled trials (RCTs) or quasi-RCTs. 22 trials (n = 101 507) met the selection criteria.
Meta-analysis showed that pneumococcal vaccination did not differ from control for definitive pneumococcal pneumonia (table). The pneumococcal vaccination group had fewer cases of presumptive
National Jewish Health, Denver, Colorado, USA
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Google Scholar
PubMed
Topic Collections
-
Immunology (including allergy)
-
Drugs: infectious diseases
-
Vaccination / immunisation
-
Pneumonia (infectious disease)
-
TB and other respiratory infections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
