TREATMENT
Normal food at will and nil-by-mouth enteral feeding after major upper GI surgery did not differ for mortality or morbidity
| The first 150 words of the full text of this article appear below. |
K Lassen
Dr K Lassen, University Hospital Northern Norway, Tromso, Norway; lassen@unn.no
Does allowing normal food at will increase morbidity compared with "nil-by-mouth" enteral tube feeding (ETF) after major upper gastrointestinal (GI) surgery?
Design: randomised controlled trial (RCT).
Allocation: concealed.
Blinding: {unblinded}.*
Follow-up period: 8 weeks.
Setting: 5 referral centres in Norway.
Patients: 453 patients (mean age 64 y, 59% men, based on 447 patients) who had major upper GI surgery. Exclusion criteria included severe extra-abdominal disease or trauma, life expectancy <3 months, or indications for parenteral nutrition.
Interventions: normal food at will (n = 220) or ETF by needle-catheter jejunostomy (n = 227) after surgery. ETF consisted of nutrition, 20 ml/h on day 1, increasing by 20 ml/h/d (if tolerated) up to 80 ml/h; after 5 days, patients were allowed food at will.
Outcomes:
mortality, major complications (including bacteraemia, sepsis, pneumonia, wound rupture, and pancreatitis). Secondary outcomes included minor
New York University College of Nursing, New York, New York, USA
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