TREATMENT
A nurse-delivered intervention was effective for depression in patients with cancer
| The first 150 words of the full text of this article appear below. |
M Sharpe
Professor M Sharpe, University of Edinburgh, Edinburgh, UK; Michael.Sharpe@ed.ac.uk
What is the effectiveness of a complex, nurse-delivered intervention for treating major depression in patients with cancer?
Design: randomised controlled trial (RCT) (Symptom Management Research Trials [SMaRT]).
Allocation: {concealed}.*
Blinding: blinded {data collectors, outcome assessors, data analysts, and safety committee}.*
Follow-up period: 12 months.
Setting: a regional cancer centre in the UK.
Patients:
200 outpatients (mean age 57 y, 71% women) who had cancer with prognosis 
6 months and major depressive disorder (Symptom Checklist [SCL]-20 score 1.75) for 1 month. Exclusion criteria included epilepsy, concurrent intensive anticancer treatment (eg, frequent chemotherapy or radiotherapy), and receipt of specialist psychiatric care.
Intervention:
a nurse-delivered intervention plus usual care (n = 101) or usual care alone (n = 99). The intervention consisted of up to ten 45-minute one-on-one patient education sessions about depression, treatment (including antidepressant medication), and coping strategies; 3 monthly
University of Western Ontario and Lawson Health Research Institute, London, Ontario, Canada
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