PROGNOSIS
Chorioamnionitis, gestational age, male sex, birth weight, and illness severity predicted positive autism screening scores in very-low-birth-weight preterm infants
| The first 150 words of the full text of this article appear below. |
C Limperopoulos
Dr C Limperopoulos, Montreal Children’s Hospital, Montreal, Quebec, Canada; catherine.limperopoulos@childrens.harvard.edu
What are the prevalence and risk factors of early autistic features in young children who had very low birth weights?
Design: inception cohort of preterm infants followed up to 18–24 months of age adjusted for prematurity.
Setting: {a hospital in Boston, Massachusetts, USA}.*
Patients: consecutive series of 103 preterm infants with birth weights <1500 g (median gestational age 26 wks, 60% boys, median birth weight 890 g). Exclusion criteria were known or suspected cerebral dysgenesis, dysmorphic syndromes, or chromosomal disorders. 8 infants died, and 4 were lost to follow-up.
Prognostic factors: maternal age and temperature, acute intrapartum or antepartum haemorrhage, preterm labour, placental infection, gestational age at birth, birth weight, sex, admission Score of Neonatal Acute Physiology II (SNAP-II), duration of oxygen requirement, and abnormal magnetic resonance imaging studies.
Outcomes:
included positive screening for early autistic features (failure
McMaster University, School of Nursing, Hamilton, Ontario, Canada
University of Alberta, Department of Paediatrics, Edmonton, Alberta, Canada
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Child and adolescent psychiatry (paedatrics)
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