TREATMENT
Review: topical permethrin was more effective than topical crotamiton or lindane for scabies
| The first 150 words of the full text of this article appear below. |
M Strong
Dr M Strong, University of Sheffield, Sheffield, UK; m.strong@sheffield.ac.uk
Which topical or systemic drugs are effective for scabies?
Data sources: Medline, EMBASE/Excerpta Medica, LILACS, INDMED, and Cochrane Infectious Diseases Group Specialised Register (all to February 2007); Cochrane Central Register of Controlled Trials (Cochrane Library, Issue 1, 2007); websites of registered clinical trials and grey literature sources (March 2007); and reference lists.
Study selection and assessment:
randomised controlled trials (RCTs) that compared systemic or local drug treatment with placebo, no intervention, or a different intervention or combination of interventions in children or adults with a clinical or parasitological diagnosis of scabies, or their contacts. 20 RCTs (n = 2392, follow-up range 1 wk to 1 mo) met the selection criteria; 17 were done in resource-poor countries. 6 trials described an adequate method of generating the random allocation sequence, 6 reported adequate allocation concealment, and 12 reported blinding.
Sherbourne Health Centre, Toronto, Ontario, Canada
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