Treatment
Review: sparse good quality evidence supports the use of alternative therapies for menopausal symptoms
Nedrow A, Miller J, Walker M, et al. Complementary and alternative therapies for the management of menopause-related symptoms: a systematic evidence review. Arch Intern Med 2006;166:145365.
Q Are complementary and alternative therapies effective for menopausal symptoms?
Key Words: complementary therapies hot flashes menopause
| The first 150 words of the full text of this article appear below. |
Data sources:
Medline, PsycINFO, Cochrane Library (to March 2005), AMED, MANTIS, reference lists, experts, and websites.
Study selection and assessment:
randomised, placebo controlled trials and meta-analyses that evaluated alternative therapies (categorised by the National Center for Complementary and Alternative Medicine) in perimenopausal and postmenopausal women (including those with breast cancer). 70 randomised controlled trials (RCTs) met the selection criteria: 48 assessed biologically based therapies (including 31 of phytoestrogens), 9 assessed mind-body therapies, 1 assessed manipulative therapy, 2 assessed energy therapies, and 10 assessed whole medical systems. Methodological quality of most RCTs was fair or poor.
Outcomes:
improvement in menopausal symptoms (eg, hot flashes, sleep disturbance, vaginal dryness, urinary frequency or incontinence, depression, anxiety, and sexual dysfunction), quality of life, and cognitive function.
A few RCTs showed more improvement with treatment than with placebo for hot flashes, other menopausal symptoms, and cognitive functioning (table), but the evidence was inconsistent.
There is
Sinclair School of Nursing, University of Missouri, Columbia
Missouri, USA
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